CD36, Mouse, FITC, Clone: TR9, Abnova™

Catalog No.	Quantity
89-111-811	100 Reactions

Catalog No. 89-111-811 Supplier Abnova Corporation Supplier No. MAB4415

Description

Mouse monoclonal antibody raised against native CD36.

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CD36
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: TR9
• Conjugate: FITC
• Description: Mouse monoclonal antibody raised against native CD36.
• Dilution: Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: CD36
• Gene Alias: CHDS7/FAT/GP3B/GP4/GPIV/PASIV/SCARB3
• Gene Symbols: CD36
• Host Species: Mouse
• Immunogen: Native purified CD36 from human platelets.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 948
• Test Specificity: This antibody reacts with CD36 (GPIIIb), a 85 KDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. This antibody TR9 cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells).
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1