CD3E, Mouse, Clone: CA-3, Abnova™

Catalog No.	Quantity
89-110-428	100 μg

Catalog No. 89-110-428 Supplier Abnova Corporation Supplier No. MAB1433

Description

Mouse monoclonal antibody raised against native CD3E.

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq

Specifications

• Antigen: CD3E
• Applications: Immunohistochemistry (Frozen)
• Classification: Monoclonal
• Clone: CA-3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native CD3E.
• Dilution: Immunohistochemistry (Frozen sections) (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)
• Gene: CD3E
• Gene Alias: FLJ18683/T3E/TCRE
• Gene Symbols: CD3E
• Host Species: Mouse
• Immunogen: Native purified CD3E from human thymocytes followed by Sezary T cells.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 916
• Target Species: Human, Rat
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1