CD3E, Mouse, Clone: MEM-57, Abnova™

Catalog No.	Quantity
89-108-201	100 μg

Catalog No. 89-108-201 Supplier Abnova Corporation Supplier No. MAB0870

Description

Mouse monoclonal antibody raised against native CD3E.

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq

Specifications

• Antigen: CD3E
• Applications: Flow Cytometry, Immunoprecipitation
• Classification: Monoclonal
• Clone: MEM-57
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native CD3E.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: CD3E
• Gene Alias: FLJ18683/T3E/TCRE
• Gene Symbols: CD3E
• Host Species: Mouse
• Immunogen: Native purified CD3E from human thymocytes and T lymphocytes.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 916
• Test Specificity: This antibody reacts with gamma-epsilon and delta-epsilon dimers of human CD3 complex, a part of a bigger multisubunit T cell receptor complex (CD3/TCR) expressed on peripheral blood T lymphocytes and mature thymocytes.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a