CD44, Mouse, APC, Clone: MEM-263, Abnova™

Catalog No.	Quantity
89-112-899	100 Reactions

Catalog No. 89-112-899 Supplier Abnova Corporation Supplier No. MAB6490

Description

Mouse monoclonal antibody raised against native CD44.

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq

Specifications

• Antigen: CD44
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: MEM-263
• Conjugate: APC
• Description: Mouse monoclonal antibody raised against native CD44.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: CD44
• Gene Alias: CDW44/CSPG8/ECMR-III/HCELL/IN/LHR/MC56/MDU2/MDU3/MGC10468/MIC4/MUTCH-I/Pgp1
• Gene Symbols: CD44
• Host Species: Mouse
• Immunogen: Native purified CD44 from African Green Monkey COS-7 cells.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 960
• Test Specificity: This antibody reacts with extracellular (N-terminal) domain of standard CD44 (Phagocyte glycoprotein 1), a 80-95 KDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells,etc.); it is negative on platelets and hepatocytes.
• Target Species: Canine, Human, Monkey, Pig
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1