CD44, Mouse, FITC, Clone: MEM-85, Abnova™

Mouse monoclonal antibody raised against native CD44.

Supplier:  Abnova Corporation MAB4568

Catalog No. 89-111-905

Description

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq

Specifications

• Antigen: CD44
• Classification: Monoclonal
• Conjugate: FITC
• Dilution: Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Gene: CD44
• Gene Symbols: CD44
• Immunogen: Native purified CD44 from leukocytes of patient suffering from LGL-type leukaemia.
• Regulatory Status: RUO
• Gene ID (Entrez): 960
• Target Species: Human
• Form: Liquid

• Applications: Flow Cytometry
• Clone: MEM-85
• Description: Mouse monoclonal antibody raised against native CD44.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene Alias: CDW44/CSPG8/ECMR-III/HCELL/IN/LHR/MC56/MDU2/MDU3/MGC10468/MIC4/MUTCH-I/Pgp1
• Host Species: Mouse
• Quantity: 100 Reactions
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with both cell surface-expressed and soluble form of CD44 antigen (Phagocyte glycoprotein 1), a 80-95 KDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes.
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2b