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CD45 Mouse anti-Rat, Alexa Fluor 647, Clone: OX-1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565465

Catalog No. BDB565465


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Description

Description

The OX-1 antibody recognizes all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

Specifications

Specifications

CD45
OX-1
Alexa Fluor 647
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Rat
Flow Cytometry
0.2mg/mL
Ptprc; Lca; Leucocyte common antigen; RT7; T200
Affinity Purified
Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes
Affinity Chromatography
RUO
Primary
24699
Documents
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