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CD45 Mouse anti-Rat, Alexa Fluor 647, Clone: OX-1, BD

Catalog No. BDB565465 Shop All BD Biosciences Products
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BDB565465 50 μg
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Catalog No. BDB565465 Supplier BD Biosciences Supplier No. 565465

Description

Mouse Monoclonal Antibody

The OX-1 antibody recognizes all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD45
Applications Flow Cytometry
Classification Monoclonal
Clone OX-1
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Description Ptprc; Lca; Leucocyte common antigen; RT7; T200
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24699
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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