CD46, Mouse, Clone: 122.2, Abnova™

Catalog No.	Quantity
89-110-280	100 μg

Catalog No. 89-110-280 Supplier Abnova Corporation Supplier No. MAB12137

Description

Mouse monoclonal antibody raised against recombinant human CD46.

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CD46
• Applications: Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: 122.2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant human CD46.
• Dilution: Flow Cytometry Immunohistochemistry (0.5-1 ug/mL) Western blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
• Gene: CD46
• Gene Alias: MCP/MGC26544/MIC10/TLX/TRA2.10
• Gene Symbols: CD46
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human CD46.
• Purification Method: Protein A/G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4179
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ