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Description
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | CD47 |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | B6H12.2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against full length CD47. |
| Dilution | Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Frozen sections) (0.5-1 ug/mL for 30 min at RT) Immunoprecipitation (1-2 ug/500 ug protein) Western Blot (0.25-0.5 ug/mL) The optimal working dilut |
| Formulation | In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide) |
| Gene | CD47 |
| Gene Alias | IAP/MER6/OA3 |
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