CD55, Mouse, Clone: MEM-118, Abnova™

Mouse monoclonal antibody raised against native CD55.

Supplier:  Abnova Corporation MAB0893

Catalog No. 89-108-223

Description

This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq

Specifications

• Antigen: CD55
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: CD55
• Gene Symbols: CD55
• Immunogen: Native purified CD55 from human T cell line HPB-ALL.
• Regulatory Status: RUO
• Gene ID (Entrez): 1604
• Target Species: Human, Primate
• Form: Liquid

• Applications: Flow Cytometry, Immunoprecipitation
• Clone: MEM-118
• Description: Mouse monoclonal antibody raised against native CD55.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Alias: CR/CROM/DAF/TC
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgM