CD59, Mouse, Clone: VJ1/12.2, Abnova™

Catalog No.	Quantity
89-112-039	100 μg

Catalog No. 89-112-039 Supplier Abnova Corporation Supplier No. MAB4990

Description

Mouse monoclonal antibody raised against native CD59.

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq

Specifications

• Antigen: CD59
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: VJ1/12.2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native CD59.
• Dilution: Flow Cytometry (20 uL/10⁶ cells) The optimal working dilution should be determined by the end user.
• Formulation: In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
• Gene: CD59
• Gene Alias: 16.3A5/1F5/EJ16/EJ30/EL32/FLJ38134/FLJ92039/G344/HRF-20/HRF20/MAC-IP/MACIF/MEM43/MGC2354/MIC11/MIN1/MIN2/MIN3/MIRL/MSK21/p18-20
• Gene Symbols: CD59
• Host Species: Mouse
• Immunogen: Cell preparation of human peripheral blood lymphocytes.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 966
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Avoid prolonged exposure to light.
• Form: Liquid
• Isotype: IgG2a