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CD64 Mouse anti-Human, PE-CF594, Clone: 10.1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565389

Catalog No. BDB565389


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Description

Description

The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.

Specifications

Specifications

CD64
10.1
FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1
Affinity Purified
Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes
Affinity Chromatography
RUO
Primary
Human
Flow Cytometry
PE-CF594
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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