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CD64 Mouse anti-Human, PE-CF594, Clone: 10.1, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 565389
Description
The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.
Specifications
CD64 | |
Monoclonal | |
PE-CF594 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes | |
50 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
10.1 | |
FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1 | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
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