CD68, Mouse, Clone: KP1, Abnova™

Mouse monoclonal antibody raised against CD68.

Supplier:  Abnova Corporation MAB11303

Catalog No. 89-109-467

Description

This gene encodes a 110kDa transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: CD68
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CD68
• Gene Symbols: CD68
• Immunogen: A subcellular fraction of human alveolar macrophages.
• Regulatory Status: RUO
• Gene ID (Entrez): 968
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (PFA fixed)
• Clone: KP1
• Description: Mouse monoclonal antibody raised against CD68.
• Formulation: Bioreactor concentrate (0.05% sodium azide)
• Gene Alias: DKFZp686M18236/GP110/SCARD1
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid