CD68, Mouse, Clone: SPM130, Abnova™

Catalog No.	Quantity
89-110-176	100 μg

Catalog No. 89-110-176 Supplier Abnova Corporation Supplier No. MAB12032

Description

Mouse monoclonal antibody raised against CD68.

This gene encodes a 110kDa transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: CD68
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: SPM130
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against CD68.
• Dilution: Immunohistochemistry (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide)
• Gene: CD68
• Gene Alias: DKFZp686M18236/GP110/SCARD1
• Gene Symbols: CD68
• Host Species: Mouse
• Immunogen: Subcellular fraction of human alveolar macrophages.
• Purification Method: Protein A/G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 968
• Test Specificity: Does not react with chicken, dog, and pig.
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ