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CD8 beta Antibody (BU88), Novus Biologicals™
SDP

Catalog No. NBP24475301 Shop All R&D Systems Products
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NBP24475301 0.1 mg
NBP24475300 0.02 mg
NBP24475302 0.2 mg
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Catalog No. NBP24475301 Supplier Novus Biologicals Supplier No. NBP2447530.1MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD8 beta Monoclonal specifically detects CD8 beta in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen CD8 beta
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone BU88
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Gene Symbols CD8B
Host Species Mouse
Immunogen Human CD8 beta
Molecular Weight of Antigen 32 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 926
Test Specificity The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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