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CD8, Mouse, Clone: C8/144B, Abnova™

Catalog No. 89108941 Shop All Abnova Corporation Products
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89-108-941 1 mL
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Catalog No. 89-108-941 Supplier Abnova Corporation Supplier No. MAB10739
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Description

Mouse monoclonal antibody raised against CD8.

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen CD8
Applications Immunohistochemistry
Classification Monoclonal
Clone C8/144B
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against CD8.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (protein base, 0.09% sodium azide)
Gene CD8A
Gene Alias CD8/Leu2/MAL/p32
Gene Symbols CD8A
Host Species Mouse
Immunogen CD8.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 925
Content And Storage Store at 4°C is stable for 3 years.
Form Liquid
Isotype IgG1 κ
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