CD86, Mouse, Clone: 1B3, Abnova™

Mouse monoclonal antibody raised against partial recombinant CD86.

Supplier:  Abnova Corporation MAB10541

Catalog No. 89-108-730

Description

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq

Specifications

• Antigen: CD86
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Gene: CD86
• Gene Symbols: CD86
• Immunogen: Recombinant protein corresponding to human CD86.
• Regulatory Status: RUO
• Gene ID (Entrez): 942
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 1B3
• Description: Mouse monoclonal antibody raised against partial recombinant CD86.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: B7-2/B70/CD28LG2/LAB72/MGC34413
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid