CD97, Mouse, FITC, Clone: MEM-180, Abnova™

Catalog No.	Quantity
89-112-069	100 Reactions

Catalog No. 89-112-069 Supplier Abnova Corporation Supplier No. MAB5039

Description

Mouse monoclonal antibody raised against native CD97.

This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found. [provided by RefSeq

Specifications

• Antigen: CD97
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: MEM-180
• Conjugate: FITC
• Description: Mouse monoclonal antibody raised against native CD97.
• Dilution: Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: CD97
• Gene Alias: TM7LN1
• Gene Symbols: CD97
• Host Species: Mouse
• Immunogen: Native purified CD97 from PHA-activated peripheral blood cells.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 976
• Test Specificity: This antibody recognizes an unique epitope on CD97, a 75-85 KDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1