CDC42, Mouse, Clone: 1, Abnova™

Catalog No.	Quantity
89-113-884	100 μg

Catalog No. 89-113-884 Supplier Abnova Corporation Supplier No. MAB9926

Description

Mouse monoclonal antibody raised against full-length recombinant CDC42.

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: CDC42
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant CDC42.
• Dilution: Western blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
• Gene: CDC42
• Gene Accession No.: NM_044472.2
• Gene Alias: CDC42Hs/G25K
• Gene Symbols: CDC42
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human CDC42.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 998
• Test Specificity: It can expression in SW480 whole cell lysate.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b