CDC42, Mouse, Clone: 56a45, Abnova™

Catalog No.	Quantity
89-113-587	100 μL

Catalog No. 89-113-587 Supplier Abnova Corporation Supplier No. MAB8796

Description

Mouse monoclonal antibody raised against full-length recombinant CDC42.

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: CDC42
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 56a45
• Concentration: 1 ug/uL
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant CDC42.
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
• Gene: CDC42
• Gene Alias: CDC42Hs/G25K
• Gene Symbols: CDC42
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human CDC42.
• Purification Method: Affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 998
• Test Specificity: This antibody recognizes recombinant protein CDC42.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1