CDH1, Mouse, Clone: 7A2, Abnova™

Catalog No.	Quantity
89-108-736	100 μL

Catalog No. 89-108-736 Supplier Abnova Corporation Supplier No. MAB10547

Description

Mouse monoclonal antibody raised against partial recombinant CDH1.

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq

Specifications

• Antigen: CDH1
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 7A2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant CDH1.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: CDH1
• Gene Alias: Arc-1/CD324/CDHE/ECAD/LCAM/UVO
• Gene Symbols: CDH1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human CDH1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 999
• Target Species: Human, Monkey, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1