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CDH1, Mouse, Clone: SPM471, Abnova™

Catalog No. 89110834 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-110-834 100 μL
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Catalog No. 89-110-834 Supplier Abnova Corporation Supplier No. MAB2127

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse monoclonal antibody raised against partial recombinant CDH1.

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq

Specifications

Antigen CDH1
Applications Immunohistochemistry
Classification Monoclonal
Clone SPM471
Conjugate Unconjugated
Description cadherin 1, type 1, E-cadherin (epithelial)
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene CDH1
Gene Alias Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Gene Symbols CDH1
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 600-707 of human CDH1.
Purification Method Protein A purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 999
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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