CDKN2B, Mouse, Clone: DCS114, Abnova™

Catalog No.	Quantity
89-110-772	100 μg

Catalog No. 89-110-772 Supplier Abnova Corporation Supplier No. MAB2030

Description

Mouse monoclonal antibody raised against full-length recombinant CDKN2B.

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq

Specifications

• Antigen: CDKN2B
• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: DCS114
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant CDKN2B.
• Dilution: Western blot (1 to 5 ug /mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.08% sodium azide)
• Gene: CDKN2B
• Gene Alias: CDK4I/INK4B/MTS2/P15/TP15/p15INK4b
• Gene Symbols: CDKN2B
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human CDKN2B.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1030
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1