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Description
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM
Specifications
Specifications
| Antigen | COBRA1 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against full length recombinant COBRA1. |
| Dilution | Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.05% sodium azide) |
| Gene | COBRA1 |
| Gene Alias | DKFZp586B0519/KIAA1182/NELF-B/NELFB |
| Gene Symbols | COBRA1 |
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