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COL17A1, Mouse, Clone: B1052M, Abnova™

Catalog No. 89111654 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-111-654 100 μg
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Catalog No. 89-111-654 Supplier Abnova Corporation Supplier No. MAB3963

Description

Mouse monoclonal antibody raised against recombinant COL17A1.

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq

Specifications

Antigen COL17A1
Applications ELISA, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone B1052M
Conjugate Unconjugated
Description collagen, type XVII, alpha 1
Formulation Lyophilized from 50mM Tris, pH 7.4
Gene COL17A1
Gene Alias BA16H23.2, BP180, BPAG2, FLJ60881, KIAA0204, LAD-1
Gene Symbols COL17A1
Host Species Mouse
Immunogen Recombinant GST fusion protein corresponding to amino acids 1-490 of human COL17A1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1308
Target Species Human
Content And Storage Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG2a
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