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Description
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq
Specifications
Specifications
| Antigen | COMP |
| Applications | ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 6G5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against COMP. |
| Dilution | ELISA (1:5-1:10) Western Blot (1:1-1:3) The optimal working dilution should be determined by the end user. |
| Formulation | In culture supernatant (0.01% sodium azide) |
| Gene | COMP |
| Gene Alias | EDM1/EPD1/MED/MGC131819/MGC149768/PSACH/THBS5 |
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