MilliporeSigma™ Mouse anti-Coronin-1A, Clone: 2E4.1,

Catalog No.	Quantity
MABN319MI	100 μg

Catalog No. MABN319MI Supplier MilliporeSigma™ Supplier No. MABN319

Description

Mouse Monoclonal Antibody

Specifically detects Coronin-1A clone: 2E4.1 in Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry

Coronin-1A (also known as clipin-A, coronin-1, coronin-like protein, Acoronin-like protein p57, tryptophan aspartate-containing coat protein) is a cytoplasmic protein encoded by the CORO1A gene in human (also known as CLABP, CLIPINA, HCORO1, IMD8, TACO). It is a member of the WD repeat protein family of proteins that are reported to be involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Coronin-1A is reported to be a component of the phagosome coat that is normally released prior to maturation into lysosomes. Mycobacteria are reported to evade host defense by recruiting and retaining coronin-1A on phagosomes, while in coronin-1A-lacking macrophages, mycobacteria are readily transported to lysosomes for degradation (PMID 10338208).

Specifications

• Antigen: Coronin-1A
• Applications: Immunocytochemistry, Immunohistochemistry
• Classification: Monoclonal
• Clone: 2E4.1
• Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: P31146
• Gene Symbols: CORO1A; CORO1
• Host Species: Mouse
• Immunogen: GST-tagged recombinant protein corresponding to human Coronin-1A.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Neuroscience
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_001180262
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG1 κ

For Research Use Only