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Description
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | CPB2 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against native CPB2. |
| Dilution | Western Blot (5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (50% glycerol) |
| Gene | CPB2 |
| Gene Alias | CPU/PCPB/TAFI |
| Gene Symbols | CPB2 |
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