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CR1, Mouse, Clone: KT23, Abnova™

Catalog No. 89110566 Shop All Abnova Corporation Products
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100 μg
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89-110-566 100 μg
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Catalog No. 89-110-566 Supplier Abnova Corporation Supplier No. MAB1670
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Description

Mouse monoclonal antibody raised against partial recombinant CR1.

This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq]

Specifications

Antigen CR1
Applications Flow Cytometry
Classification Monoclonal
Clone KT23
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant CR1.
Dilution Flow Cytometry (1 ug/100 ul) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene CR1
Gene Alias C3BR/CD35/KN
Gene Symbols CR1
Host Species Mouse
Immunogen Recombinant protein corresponding to extracellular reagion of human CR1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1378
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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