CRK, Mouse, Clone: 3G11E8, Abnova™

Catalog No.	Quantity
89-108-765	100 μL

Catalog No. 89-108-765 Supplier Abnova Corporation Supplier No. MAB10573

Description

Mouse monoclonal antibody raised against partial recombinant CRK.

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq

Specifications

• Antigen: CRK
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 3G11E8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant CRK.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: CRK
• Gene Alias: CRKII
• Gene Symbols: CRK
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human CRK.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1398
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b