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Description
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic
Specifications
Specifications
| Antigen | CRKL |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant CRKL. |
| Formulation | 50% glycerol |
| Gene | CRKL |
| Gene Accession No. | NM_005207 |
| Gene Symbols | CRKL |
| Host Species | Mouse |
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