CST3, Mouse, Clone: 5H2, Abnova™

Catalog No.	Quantity
89-108-812	100 μL

Catalog No. 89-108-812 Supplier Abnova Corporation Supplier No. MAB10618

Description

Mouse monoclonal antibody raised against partial recombinant CST3.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq

Specifications

• Antigen: CST3
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 5H2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant CST3.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: CST3
• Gene Alias: ARMD11/MGC117328
• Gene Symbols: CST3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human CST3.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1471
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1