CTCF, Mouse, Clone: 1D11, Abnova™

Mouse monoclonal antibody raised against partial recombinant CTCF.

Supplier:  Abnova Corporation MAB10575

Catalog No. 89-108-767

Description

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq]

Specifications

• Antigen: CTCF
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Gene: CTCF
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 1D11
• Description: Mouse monoclonal antibody raised against partial recombinant CTCF.
• Formulation: In ascites (0.03% sodium azide)
• Gene Symbols: CTCF
• Immunogen: Recombinant protein corresponding to human CTCF.
• Regulatory Status: RUO
• Gene ID (Entrez): 10664
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1