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CTNNB1, Mouse, Clone: 4D5, Abnova™

Catalog No. 89108813 Shop All Abnova Corporation Products
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89-108-813 100 μL
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Catalog No. 89-108-813 Supplier Abnova Corporation Supplier No. MAB10619
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Description

Mouse monoclonal antibody raised against partial recombinant CTNNB1.

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM

Specifications

Antigen CTNNB1
Applications ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 4D5
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant CTNNB1.
Dilution ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
Formulation In ascites (0.03% sodium azide)
Gene CTNNB1
Gene Alias CTNNB/DKFZp686D02253/FLJ25606/FLJ37923
Gene Symbols CTNNB1
Host Species Mouse
Immunogen Recombinant protein corresponding to human CTNNB1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1499
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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