CTSC, Mouse, Clone: 97a6, Abnova™

Mouse monoclonal antibody raised against full-length recombinant CTSC.

Supplier:  Abnova Corporation MAB8780

Catalog No. 89-113-581

Description

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CTSC
• Classification: Monoclonal
• Concentration: 1 ug/uL
• Description: Mouse monoclonal antibody raised against full length recombinant CTSC.
• Formulation: In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
• Gene Alias: CPPI/DPP1/DPPI/HMS/JP/JPD/PALS/PLS
• Host Species: Mouse
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1075
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 97a6
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: CTSC
• Gene Symbols: CTSC
• Immunogen: Recombinant protein corresponding to full length human CTSC.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes recombinant protein CTSC.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2b