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Description
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq
Specifications
Specifications
| Antigen | CTSD |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | CTD-19 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against native CTSD. |
| Dilution | Western Blot (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide) |
| Gene | CTSD |
| Gene Alias | CLN10/CPSD/MGC2311 |
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