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Description
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | CUGBP1 |
| Applications | Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 3B1 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against CUGBP1. |
| Dilution | Western Blot (1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In buffer containing 0.09% sodium azide |
| Gene | CUGBP1 |
| Gene Alias | BRUNOL2/CUG-BP/CUGBP/NAB50/hNab50 |
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