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Mouse anti-Cyclin A2, Clone: E67, Azide Free, Novus Biologicals™
SDP

Catalog No. p-5322281 Shop All R&D Systems Products
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0.2 mg
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Catalog No. Quantity
NBP23461302 0.2 mg
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Catalog No. NBP23461302 Supplier Novus Biologicals Supplier No. NBP2346130.2 MG

Description

Mouse Monoclonal Antibody

Cyclin A2 Monoclonal antibody specifically detects Cyclin A2 in Human, Mouse, Bovine, Mustelid, Primate samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

Antigen Cyclin A2
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone E67
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin 1-2ug/ml, Immunohistochemistry-Frozen 1-2ug/ml, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. P20248
Gene Alias CCN1CCNAcyclin-A, cyclin A2, Cyclin-A, cyclin-A2
Gene Symbols CCNA2
Host Species Mouse
Immunogen Full length bovine Cyclin A protein
Molecular Weight of Antigen 54 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 890
Test Specificity It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
Reconstitution Protein A purified
Target Species Human, Mouse, Bovine, Mustelid, Primate
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2a κ
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For Research Use Only

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