MilliporeSigma™ Mouse anti-CYP11B2, Clone: 41-17B,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABS1251

Catalog No. MABS1251MI

Description

Specifically detects CYP11B2 clone: 41-17B in Human samples, and it is validated for Western Blotting

Cytochrome P450 11B2, mitochondrial (EC1.14.15.4, EC1.14.15.5; UniProt P19099; also known as ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, Cytochrome P450 subfamily XIB polypeptide 2, Steroid 11-beta-monooxygenase, Steroid 11-beta/18-hydroxylase, Mitochondrial cytochrome P450 family 11 subfamily B polypeptide 2) is encoded by the CYP11B2 (Also known as CPN2, CYP11B, CYP11BL, P450C18) gene in human (Gene ID 1585). CYP11B2 protein is a member of the cytochrome P450 superfamily of monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11B2 protein is localized to the mitochondrial inner membrane and exhibits steroid 18-hydroxylase activity and steroid 11 beta-hydroxylase activity. CYP11B2 gene mutations are known causes of corticosterone methyl oxidase 1 (CMO-1) deficiency, an autosomal recessive disorder of aldosterone biosynthesis.

Specifications

• Antigen: CYP11B2
• Classification: Monoclonal
• Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: CYP11B2
• Immunogen: Chicken serum albumin-conjugated linear peptide corresponding to human CYP11B2 near the N-terminus.
• Quantity: 100 μg
• Research Discipline: Signaling
• Gene ID (Entrez): NP_000489
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: 41-17B
• Gene Accession No.: P19099
• Host Species: Mouse
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

For Research Use Only