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Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq
Specifications
Specifications
| Antigen | CYP26A1 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | F27 P6 A1 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against synthetic peptide of CYP26A1. |
| Dilution | Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.08% sodium azide) |
| Gene | CYP26A1 |
| Gene Alias | CP26/CYP26/P450RAI/P450RAI1 |
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