CYP2A6, Mouse, Clone: F16 P2 D8, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of CYP2A6.

Supplier:  Abnova Corporation MAB1858

Catalog No. 89-110-673

Description

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq

Specifications

• Antigen: CYP2A6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CYP2A6
• Gene Symbols: CYP2A6
• Immunogen: A synthetic peptide corresponding to C-terminus of human CYP2A6.
• Regulatory Status: RUO
• Gene ID (Entrez): 1548
• Form: Liquid

• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: F16 P2 D8
• Description: Mouse monoclonal antibody raised against synthetic peptide of CYP2A6.
• Formulation: In PBS (0.08% sodium azide)
• Gene Alias: CPA6/CYP2A/CYP2A3/P450C2A/P450PB
• Host Species: Mouse
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1