CYP3A5, Mouse, Clone: F18 P3 B6, Abnova™

Catalog No.	Quantity
89-110-674	200 μg

Catalog No. 89-110-674 Supplier Abnova Corporation Supplier No. MAB1859

Description

Mouse monoclonal antibody raised against synthetic peptide of CYP3A5.

This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. [provided by RefSeq

Specifications

• Antigen: CYP3A5
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: F18 P3 B6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of CYP3A5.
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.08% sodium azide)
• Gene: CYP3A5
• Gene Alias: CP35/P450PCN3/PCN3
• Gene Symbols: CYP3A5
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to C-terminus of human CYP3A5.
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1577
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1