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Description
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq
Specifications
Specifications
| Antigen | DAD1 |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | S1 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full-length recombinant DAD1. |
| Formulation | ascites with no preservative |
| Gene | DAD1 |
| Gene Accession No. | BC007403 |
| Gene Alias | OST2 |
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