DAXX, Mouse, Clone: 7A11, Abnova™

Catalog No.	Quantity
89-108-816	100 μL

Catalog No. 89-108-816 Supplier Abnova Corporation Supplier No. MAB10621

Description

Mouse monoclonal antibody raised against partial recombinant DAXX.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: DAXX
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 7A11
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant DAXX.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol, 0.03% sodium azide)
• Gene: DAXX
• Gene Alias: BING2/DAP6/EAP1/MGC126245/MGC126246
• Gene Symbols: DAXX
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human DAXX.
• Purification Method: Protein G purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1616
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1