DDR2, Mouse, Clone: 3B11E4, Abnova™

Catalog No.	Quantity
89-108-817	100 μL

Catalog No. 89-108-817 Supplier Abnova Corporation Supplier No. MAB10622

Description

Mouse monoclonal antibody raised against partial recombinant DDR2.

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Specifications

• Antigen: DDR2
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 3B11E4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant DDR2.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: DDR2
• Gene Alias: MIG20a/NTRKR3/TKT/TYRO10
• Gene Symbols: DDR2
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human DDR2.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4921
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a