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Description
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq
Specifications
Specifications
| Antigen | DOCK4 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3E7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant DOCK4. |
| Formulation | ascites with no preservative |
| Gene | DOCK4 |
| Gene Accession No. | NM_014705 |
| Gene Alias | FLJ34238/KIAA0716/MGC134911/MGC134912 |
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