MilliporeSigma™ Mouse anti-DOCK8, Clone: 10C3.2,

Catalog No.	Quantity
MABN353MI	100 μg

Catalog No. MABN353MI Supplier MilliporeSigma™ Supplier No. MABN353

Description

Mouse Monoclonal Antibody

Specifically detects DOCK8 clone: 10C3.2 in Human samples, and it is validated for Flow Cytometry, Western Blotting

Dedicator of cytokinesis protein 8 (also known as 1200017A24Rik or Epididymis luminal protein 205) is encoded by the DOCK8 gene (also known as HEL-205, MRD2, ZIR8) in human (NCBI Gene ID 81704). DOCK8 is a cytosolic scaffolding protein involved in cytoskeletal rearrangement and cell migration. DOCK8 deficiency due to genetic mutations result in combined immune deficiency, historically diagnosed as an atypical form of hyper-IgE syndrome (HIES) or autosomal recessive HIES, which remains to be the focus of ongoing DOCK8 research activities. (PMIDn20864884). Clone 10C3.2 detects an internal epitope within the C-terminal half of the DOCK8 protein (UniProt Q8NF50).

Specifications

• Antigen: DOCK8
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 10C3.2
• Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: Q8NF50
• Gene Symbols: DOCK8
• Host Species: Mouse
• Immunogen: KLH-conjugated linear peptide corresponding to human DOCK8.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Neuroscience
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_001177387
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG1 κ

For Research Use Only