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Mouse anti-DOG1/TMEM16A, Clone: DG1/447, Azide Free, Novus Biologicals™
SDP

Mouse Monoclonal Antibody

Specifications

Antigen DOG1/TMEM16A
Clone DG1/447
Concentration 1.0 mg/mL
Dilution Western Blot 0.5-1.0ug/ml, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Applications Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP23460302
SDP
View Documents
Novus Biologicals
NBP2346030.2 MG
0.2 mg Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area. N/A
Description

Description

DOG1/TMEM16A Monoclonal antibody specifically detects DOG1/TMEM16A in Human samples. It is validated for Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

DOG1/TMEM16A
1.0 mg/mL
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Human
Q5XXA6
55107
Recombinant human DOG-1 protein
Primary
Protein A purified
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
DG1/447
Western Blot 0.5-1.0ug/ml, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Monoclonal
Purified
RUO
10mM PBS - BSA free with No Preservative
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
TMEM16A
IgG1 κ
Protein A or G purified
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
SDS
Documents

Documents

Product Certifications

For Research Use Only

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