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Description
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq
Specifications
Specifications
| Antigen | DSG1 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | CA72/733 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant human DSG1. |
| Dilution | Immunohistochemistry (0.5-1 ug/mL) Western blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.05% BSA, 0.05% sodium azide) |
| Gene | DSG1 |
| Gene Alias | CDHF4/DG1/DSG |
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