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DUSP5, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89104403 Shop All Abnova Corporation Products
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89-104-403 50 μL
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Catalog No. 89-104-403 Supplier Abnova Corporation Supplier No. H00001847A01
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Mouse polyclonal antibody raised against a partial recombinant DUSP5.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq

Sequence: LKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC

Specifications

Antigen DUSP5
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant DUSP5.
Formulation 50% glycerol
Gene DUSP5
Gene Accession No. NM_004419
Gene Alias DUSP/HVH3
Gene Symbols DUSP5
Host Species Mouse
Immunogen DUSP5 (NP_004410, 286 a.a. to 384 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1847
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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