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DUSP6, Mouse, Clone: 3G2, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant DUSP6.

Supplier:  Abnova Corporation H00001848M01A

Catalog No. 89-104-407


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Description

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
Specifications

Specifications

DUSP6
Monoclonal
Unconjugated
ascites with no preservative
BC003143
DUSP6
DUSP6 (AAH03143,1 a.a. ∽ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
RUO
1848
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Ascites
ELISA, Western Blot
3G2
Mouse monoclonal antibody raised against a full-length recombinant DUSP6.
DUSP6
MKP3/PYST1
Mouse
200 μL
Primary
Human
Antibody
IgG1 κ
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